Here is some more of the latest end-time speculation nonsense from the Left Behind crowd. Really, this video was just making fun of them.
As I understand it, there are only four occurrences of the word “antichrist” in the Bible and they are all in 1 & 2 John. There are two ways one can go with “anti” – one is replacement the other is opposition. In my opinion, the context supports opposition over replacement. So in the context of 1 John “many antichrist have come” and “they went our from us” (1 Jn 2:18,19) and this is because an “antichrist” is any person who denies the Father and the Son (1 Jn 2:22) – John was clearly referring to the false teachers and any person in agreement with them because they would not acknowledge teaching that Jesus Christ had come in the flesh as the Son of God (1 John 4:3; 2 Jn 7).
So who is the antichrist? It is that person who denies that Jesus Christ came in the flesh as the Son of God from the Father. It is that person who in his or her heart intentionally leaves God out of the picture if not outright opposes the things of God.